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Increases of 510 mmHg systolic are common, with peak effect at 4 hours post-dose

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GLP-1 therapies improve insulin action and support weight loss, helping regulate cycles and boost ovulation

The report further distinguished clinical obesity, defined as excess adiposity with significant tissue or organ dysfunction that can lead to severe complications, from preclinical obesity, defined as excess adiposity without immediate organ dysfunction but with an increased risk of progression to clinical obesity and other non-communicable diseases

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